Functional Assay to Correlate Protein Oligomerization States with Membrane Pore Formation
نویسندگان
چکیده
منابع مشابه
Oligomerization and pore formation by equinatoxin II inhibit endocytosis and lead to plasma membrane reorganization.
Pore-forming toxins have evolved to induce membrane injury by formation of pores in the target cell that alter ion homeostasis and lead to cell death. Many pore-forming toxins use cholesterol, sphingolipids, or other raft components as receptors. However, the role of plasma membrane organization for toxin action is not well understood. In this study, we have investigated cellular dynamics durin...
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ژورنال
عنوان ژورنال: Analytical Chemistry
سال: 2020
ISSN: 0003-2700,1520-6882
DOI: 10.1021/acs.analchem.0c03276